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作为中毒靶点的注意力:药物滥用研究的见解与方法

Attention as a target of intoxication: insights and methods from studies of drug abuse.

作者信息

Bushnell P J, Levin E D, Marrocco R T, Sarter M F, Strupp B J, Warburton D M

机构信息

Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, 27711, Research Triangle Park, NC 27711, USA.

出版信息

Neurotoxicol Teratol. 2000 Jul-Aug;22(4):487-502. doi: 10.1016/s0892-0362(00)00077-5.

DOI:10.1016/s0892-0362(00)00077-5
PMID:10974587
Abstract

A symposium was convened to discuss recent developments in the assessment of attention and the effects of drugs and toxic chemicals on attention at the 17th annual meeting of the Behavioral Toxicology Society on May 1, 1999, in Research Triangle Park, NC. Speakers addressed issues including the methodology of assessing cognitive function, the neurobiology of specific aspects of attention, the dual roles of attention as a target of intoxication and as a mediating variable in the development of addiction to psychoactive drugs, the changes in attention that accompany neuropsychological disorders of schizophrenia, senile dementia of the Alzheimer type and attention deficit hyperactivity disorder, and potential therapies for these disorders. This article provides an overview of the objectives of the symposium, followed by summaries of each of the talks given.

摘要

1999年5月1日,行为毒理学协会第17届年会在北卡罗来纳州三角研究园召开了一次专题研讨会,讨论注意力评估的最新进展以及药物和有毒化学物质对注意力的影响。发言者探讨了多个问题,包括认知功能评估方法、注意力特定方面的神经生物学、注意力作为中毒靶点以及作为精神活性药物成瘾发展中介变量的双重作用、伴随精神分裂症、阿尔茨海默型老年痴呆症和注意力缺陷多动障碍等神经心理障碍出现的注意力变化,以及针对这些障碍的潜在治疗方法。本文先概述了研讨会的目标,随后是对每场演讲的总结。

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