Mathur A, Airan B, Bhan A, Sharma R, Sampath Kumar A, Talwar K K, Chopra P, Venugopal P
Department of Cardiothoracic & Vascular Surgery, All India Institute of Medical Sciences, New Delhi.
Indian Heart J. 2000 May-Jun;52(3):319-23.
Eighty-eight patients underwent surgery for various cardiac tumours from January 1978 to June 1998 at our Institute. Seventy-seven tumours were myxomas, 10 were non-myxomatous and one was secondary cardiac tumour. Case records of the patients with non-myxomatous primary cardiac tumours and one secondary tumour were reviewed. Six of these primary tumours were benign and four, malignant. Age of the patients ranged from 26 days to 47 years. Among patients (3 children, 8 adults) with non-myxomatous primary cardiac tumours, dyspnoea on exertion was the commonest symptom and was the cause of presentation in seven out of 11 patients. Of the eight adults, six were in New York Heart Association functional class II/III and two in class IV. Echocardiographic diagnosis was possible in all the patients. Complete excision of the tumour was possible in all benign and two of the four malignant tumours. Incomplete resection was done in the secondary tumour. Of the six benign tumours, three were rhabdomyomas and one each of fibroma, haemangioma and lipoma. The malignant tumours were one each of fibrosarcoma, angiosarcoma, unclassified sarcoma and malignant mesothelioma. The secondary tumour was a malignant thymoma. Follow-up ranged from 1 to 10 years (mean 7.2 years). Of the patients with benign tumours, four out of six are alive; one patient died on the first post-operative day and one lost to follow-up. Two of the four patients with malignant cardiac tumours died, one was lost to follow-up and one is alive two years after surgery. The patient with secondary malignant thymoma to the superior vena cava was lost to follow-up three months after an uneventful recovery from surgery.
1978年1月至1998年6月期间,我院有88例患者因各种心脏肿瘤接受了手术。其中77例为黏液瘤,10例为非黏液瘤性肿瘤,1例为继发性心脏肿瘤。回顾了非黏液瘤性原发性心脏肿瘤患者和1例继发性肿瘤患者的病例记录。这些原发性肿瘤中6例为良性,4例为恶性。患者年龄从26天至47岁不等。在患有非黏液瘤性原发性心脏肿瘤的患者(3名儿童,8名成人)中,劳力性呼吸困难是最常见的症状,11例患者中有7例以此为就诊原因。8名成人中,6例纽约心脏协会心功能分级为Ⅱ/Ⅲ级,2例为Ⅳ级。所有患者均可行超声心动图诊断。所有良性肿瘤及4例恶性肿瘤中的2例均可完整切除肿瘤。继发性肿瘤行不完全切除。6例良性肿瘤中,3例为横纹肌瘤,纤维瘤、血管瘤和脂肪瘤各1例。恶性肿瘤分别为纤维肉瘤、血管肉瘤、未分类肉瘤和恶性间皮瘤各1例。继发性肿瘤为恶性胸腺瘤。随访时间为1至10年(平均7.2年)。良性肿瘤患者中,6例中有4例存活;1例患者术后第1天死亡,1例失访。4例恶性心脏肿瘤患者中,2例死亡,1例失访,1例术后2年存活。继发于上腔静脉的恶性胸腺瘤患者术后恢复顺利,但3个月后失访。