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心脏肿瘤。20例非典型良性黏液瘤病变的临床谱及预后

Cardiac tumors. Clinical spectrum and prognosis of lesions other than classical benign myxoma in 20 patients.

作者信息

Reece I J, Cooley D A, Frazier O H, Hallman G L, Powers P L, Montero C G

出版信息

J Thorac Cardiovasc Surg. 1984 Sep;88(3):439-46.

PMID:6381889
Abstract

Between 1961 and 1983, 20 patients underwent operation at the Texas Heart Institute for primary tumors other than classical benign myxoma. Total follow-up was 70.7 patient years (mean 3.5 years). There were 10 adults and 10 children under 12 years of age. There were two operative deaths and four late deaths. All of the pediatric patients had benign lesions (five fibromas, five rhabdomyomas), and only one patient in this group died (during the operation). All operative survivors are alive between 0.9 and 18 years postoperatively, although in three cases excision was incomplete. Of the 10 adult patients, five had benign lesions; all were completely excised. In the other five adult patients, unresectable malignant tumors were found, and all four operative survivors died of metastatic disease within 8 months. Benign cardiac tumors in childhood have an excellent prognosis when completely excised and appear to have a good short-term prognosis even when excision is incomplete. Although prognosis for benign tumors in adults is good, malignant tumors are associated with very poor survival.

摘要

1961年至1983年间,20例患者在德克萨斯心脏研究所接受了手术,治疗的原发性肿瘤并非典型的良性黏液瘤。总随访时间为70.7患者年(平均3.5年)。其中有10名成人和10名12岁以下儿童。手术死亡2例,晚期死亡4例。所有儿科患者均为良性病变(5例纤维瘤,5例横纹肌瘤),该组仅1例患者死亡(手术期间)。所有手术幸存者术后存活0.9至18年,尽管有3例切除不完全。10名成年患者中,5例为良性病变,均完全切除。另外5名成年患者发现为无法切除的恶性肿瘤,4名手术幸存者均在8个月内死于转移性疾病。儿童期良性心脏肿瘤完全切除后预后极佳,即使切除不完全,短期预后似乎也良好。虽然成人良性肿瘤预后良好,但恶性肿瘤的生存率极低。

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