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[肾移植后无菌性骨坏死的影像学表现。关于30例患者的65个部位]

[Radiographic aspects of aseptic osteonecrosis following renal transplantation. Apropos of 65 localizations in 30 patients].

作者信息

Moreau J F, Arfi S, Kreis H, Pomaréde D, Heuclin C, Paolaggi J B, Michel J R

出版信息

J Radiol Electrol Med Nucl. 1975 Feb;56(2):97-110.

PMID:1097664
Abstract

The authors report 30 cases of aseptic osteonecrosis in 65 different bones, including 37 hips, 13 knees, 5 taluses, 1 cuboid, 8 shoulders, 1 humeral condyle, following renal transplantation. One patient had osteonecrosis in six different bones. In 24 cases, the necrosis occurred before the end of the 18th month following the graftmin 21 cases, radiodiagnosis of the first localisation was made before the end of the first month following the first clinical sign. The usual presenting symptom of osteonecrosis is a clear, sub-chondral crescent. In 2/3rds of cases of osteonecrosis of the femoral neck, there is a rapidly destructive form often well tolerated clinically. In 1/3rd of cases, the course was slow with mainly osteocondensation. The course is particularly destructive when, following failure of the graft, the transplanted patient is submitted to periodic hemodialysis. In 8 cases, the femoral condyles were involved, and in 4, the tibial condylesm the appearance may be that of osteochondritis dissecans, but more often the course resembles the destructive form of aseptic necrosis of the femoral head. Shoulder involvement leads to a radiological picture identical with that of the hips. One transplanted patient out of 5, has a chance to develop osteonecrosis within two years following the graft.

摘要

作者报告了65块不同骨骼中30例无菌性骨坏死病例,这些病例发生在肾移植后,包括37个髋关节、13个膝关节、5个距骨、1个骰骨、8个肩关节、1个肱骨髁。1例患者在6块不同骨骼中发生骨坏死。24例中,坏死发生在移植后18个月内;21例中,首次出现局部病变的放射学诊断在首个临床症状出现后1个月内完成。骨坏死通常的表现症状是清晰的软骨下新月形。在股骨颈骨坏死病例中,2/3为快速破坏性形式,临床上通常耐受性良好。1/3的病例病程缓慢,主要表现为骨质硬化。当移植失败后,移植患者接受定期血液透析时,病程尤其具有破坏性。8例累及股骨髁,4例累及胫骨髁,其表现可能为剥脱性骨软骨炎,但更常见的病程类似于股骨头无菌性坏死的破坏性形式。肩关节受累导致的放射学表现与髋关节相同。5例移植患者中有1例在移植后两年内有发生骨坏死的可能。

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