Sakamoto Y, Kuriwaka R, Tohjima A, Miura S
Department of Medicine, Anan Kyoei Hospital, Hanoura, Naka-gun, Tokushima, Japan.
Nihon Kokyuki Gakkai Zasshi. 2000 Jun;38(6):466-70.
A 15-year-old boy was hospitalized with complaints of fever, dry cough, and dyspnea. Chest X-ray films demonstrated diffuse infiltrates with peripheral dominance and blood gas analysis disclosed hypoxemia. Examination of bronchoalveolar lavage fluid revealed an increased eosinophil count. Transbronchial lung-biopsy specimens revealed the infiltration of eosinophils into alveolar walls. A conclusive diagnosis of acute eosinophilic pneumonia (AEP) was made on these grounds. We suspected the disease was associated with smoking because the patient had begun smoking cigarettes two weeks before admission. A challenge test was performed using a cigarette brand different from the one the patient had smoked, and was positive. Our findings supported the view that cigarette smoking in general can be a cause of AEP.
一名15岁男孩因发热、干咳和呼吸困难入院。胸部X线片显示弥漫性浸润，以外周为主，血气分析显示低氧血症。支气管肺泡灌洗液检查显示嗜酸性粒细胞计数增加。经支气管肺活检标本显示嗜酸性粒细胞浸润至肺泡壁。基于这些依据，确诊为急性嗜酸性粒细胞性肺炎（AEP）。我们怀疑该疾病与吸烟有关，因为患者在入院前两周开始吸烟。使用与患者所吸香烟不同品牌的香烟进行激发试验，结果呈阳性。我们的研究结果支持了一般情况下吸烟可导致AEP这一观点。
