制霉菌素与两性霉素B治疗义齿相关念珠菌病
Nystatin and amphotericin B in the treatment of denture-related candidiasis.
作者信息
Nairn R I
出版信息
Oral Surg Oral Med Oral Pathol. 1975 Jul;40(1):68-75. doi: 10.1016/0030-4220(75)90348-5.
PMID:1097985
Abstract
A double-blind trial of nystatin, amphotericin B, and a placebo was carried out in fifty-two cases of denture-related candidiasis and/or angular cheilitis. The drugs effected a significant clinical cure, but recurrence of the signs was common after withdrawal of the drugs. Concurrent bacteriologic examination showed few cures and continued presence of Candida albicans during the trial. A specimen from a red palate was examined histologically.
摘要
对52例与义齿相关的念珠菌病和/或口角炎患者进行了制霉菌素、两性霉素B和安慰剂的双盲试验。这些药物实现了显著的临床治愈，但停药后症状复发很常见。同时进行的细菌学检查显示治愈的病例很少，并且在试验期间白色念珠菌持续存在。对来自红色腭部的标本进行了组织学检查。
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