支气管激发试验显示的职业性过敏性空气传播接触性皮炎和环氧树脂所致的迟发性支气管哮喘。
Occupational allergic airbone contact dermatitis and delayed bronchial asthma from epoxy resin revealed by bronchial provocation test.
作者信息
Kanerva L, Estlander T, Keskinen H, Jolanki R
机构信息
Section of Occupational Dermatology, Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, FIN-00250 Helsinki, Finland.
出版信息
Eur J Dermatol. 2000 Aug;10(6):475-7.
Diglycidyl ether of bisphenol A (DGEBA) epoxy resins belong to the most common causes of occupational allergic contact dermatitis. DGEBA has on rare occasions caused occupational asthma. Here we present a patient who first developed occupational allergic contact dermatitis (ACD) caused by a single accidental exposure to DGEBA. Then, on continued occupational exposure to DGEBA, the patient developed occupational asthma from DGEBA, in addition to ACD. A bronchial provocation test with DGEBA caused a 36% drop in the peak expiratory flow, reflecting a delayed type of occupational asthma. This bronchial provocation test caused a strong dermatitis of the exposed skin of the face, in accordance with airborne ACD from DGEBA.
双酚A二缩水甘油醚（DGEBA）环氧树脂是职业性过敏性接触性皮炎最常见的病因之一。DGEBA偶尔会引发职业性哮喘。在此，我们报告一名患者，该患者最初因单次意外接触DGEBA而患上职业性过敏性接触性皮炎（ACD）。随后，在持续职业接触DGEBA的过程中，该患者除了ACD外，还因DGEBA患上了职业性哮喘。用DGEBA进行支气管激发试验导致呼气峰值流速下降36%，这反映出一种迟发型职业性哮喘。该支气管激发试验导致面部暴露皮肤出现严重皮炎，这与DGEBA引起的空气传播性ACD相符。
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