Kanerva L, Estlander T, Keskinen H, Jolanki R
Section of Occupational Dermatology, Finnish Institute of Occupational Health, Topeliuksenkatu 41 aA, FIN-00250 Helsinki, Finland.
Eur J Dermatol. 2000 Aug;10(6):475-7.
Diglycidyl ether of bisphenol A (DGEBA) epoxy resins belong to the most common causes of occupational allergic contact dermatitis. DGEBA has on rare occasions caused occupational asthma. Here we present a patient who first developed occupational allergic contact dermatitis (ACD) caused by a single accidental exposure to DGEBA. Then, on continued occupational exposure to DGEBA, the patient developed occupational asthma from DGEBA, in addition to ACD. A bronchial provocation test with DGEBA caused a 36% drop in the peak expiratory flow, reflecting a delayed type of occupational asthma. This bronchial provocation test caused a strong dermatitis of the exposed skin of the face, in accordance with airborne ACD from DGEBA.
双酚A二缩水甘油醚（DGEBA）环氧树脂是职业性过敏性接触性皮炎最常见的病因之一。DGEBA偶尔会引发职业性哮喘。在此，我们报告一名患者，该患者最初因单次意外接触DGEBA而患上职业性过敏性接触性皮炎（ACD）。随后，在持续职业接触DGEBA的过程中，该患者除了ACD外，还因DGEBA患上了职业性哮喘。用DGEBA进行支气管激发试验导致呼气峰值流速下降36%，这反映出一种迟发型职业性哮喘。该支气管激发试验导致面部暴露皮肤出现严重皮炎，这与DGEBA引起的空气传播性ACD相符。
