Machado S, Silva E, Pereira O, Sanches M, Massa A
Department of Dermatology, Hospital Geral de Santo António, Rua D. Mannell 11, Edificio ex-Cicap, 4099-001, Porto, Portugal.
Eur J Dermatol. 2000 Aug;10(6):485-6.
A 72-year-old man had noticed, in his early forties, the appearance of well-defined papulous hyperkeratotic lesions, with increasing growth, located on both sides of his feet. After twenty-five years he consulted a dermatologist for the first time. Physical examination showed annular papules and rose-coloured plaques with atrophic centres, some of them hypopigmented, with higher and irregular borders, separated from the surrounding skin by longitudinal and well-defined furrows. The lesions presented variable sizes and shapes, some of them punctate, involving exclusively and in a bilateral form, both sides, back and sole of the feet (Figs. 1 and 2). The patient did not report any subjective symptoms. He was immunocompetent and did not remember that any relative had the same disease, nor had he been subjected to radiation treatment.
一名72岁男性在四十出头时就注意到双脚两侧出现边界清晰的丘疹性角化过度病变，且病变不断增大。25年后，他首次咨询皮肤科医生。体格检查发现环形丘疹和玫瑰色斑块，中央萎缩，部分色素减退，边界更高且不规则，与周围皮肤由纵向且清晰的沟纹分隔。病变大小和形状各异，有些为点状，仅双侧累及双脚的背面和脚底（图1和图2）。患者未报告任何主观症状。他免疫功能正常，不记得有任何亲属患有相同疾病，也未接受过放射治疗。
