Vachon P, Simmerman N, Zahran A R, Carrier S
Lady Davis Institute of the Jewish General Hospital, Department of Medicine, McGill University, Montreal, Quebec, Canada.
Int J Impot Res. 2000 Feb;12(1):53-7. doi: 10.1038/sj.ijir.3900480.
The objective of this present study is to establish a model in the rat for the study of female clitoral and vaginal vascular changes during sexual excitation. A laser Doppler was used to measure blood flow changes following clitoral and pelvic plexus nerve stimulations. Results show an increase in clitoral blood flow following clitoral nerve (df1 = 12, df2 = 108, F = 21.4, P < 0.001) and pelvic plexus nerve stimulations (n = 3). A vaginal blood flow increase is also observed following pelvic plexus nerve stimulations (df1 = 12, df2 = 108, F = 4.75, P < 0.001). The female rat can therefore be used as a model for the study of the physiology, pharmacology and sexual dysfunction relating to blood flow in clitoral and vaginal tissue.
本研究的目的是在大鼠中建立一个模型,用于研究雌性阴蒂和阴道在性兴奋期间的血管变化。使用激光多普勒仪测量阴蒂和盆腔神经丛刺激后的血流变化。结果显示,阴蒂神经刺激后阴蒂血流增加(自由度1 = 12,自由度2 = 108,F = 21.4,P < 0.001),盆腔神经丛刺激后也增加(n = 3)。盆腔神经丛刺激后阴道血流也增加(自由度1 = 12,自由度2 = 108,F = 4.75,P < 0.001)。因此,雌性大鼠可作为研究阴蒂和阴道组织血流相关生理学、药理学和性功能障碍的模型。