Chan D P, Van Hare G F, Mackall J A, Carlson M D, Waldo A L
Division of Pediatric Cardiology, Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA.
Circulation. 2000 Sep 12;102(11):1283-9. doi: 10.1161/01.cir.102.11.1283.
In survivors of congenital heart surgery, intra-atrial reentrant tachycardia (IART) often develops. Previous reports have emphasized the atriotomy scar as the central barrier around which a reentrant circuit may rotate but have not systematically evaluated the atrial flutter isthmus in such patients. We sought to determine the role of the atrial flutter isthmus in supporting IART in a group of postoperative patients with congenital heart disease.
Nineteen postoperative patients with IART underwent electrophysiological studies with entrainment mapping of the atrial flutter isthmus for determining postpacing intervals. Radiofrequency ablation was performed at the identified isthmus in an effort to create a complete line of block. Twenty-one IARTs were identified in 19 patients, with a mean tachycardia cycle length of 293+/-73 ms. The atrial flutter isthmus was part of the circuit in 15 of 21 (71. 4%). In the remaining 6 of 21, the ablation target zone was at sites near atrial incisions or suture lines. Ablation was successful in 19 of 21 (90.4%) IARTs and in 14 of 15 (93.3%) cases at the atrial flutter isthmus.
In most of our postoperative patients, the atrial flutter isthmus was part of the reentrant circuit. The fact that the atrial flutter isthmus is vulnerable to ablation suggests that whenever IART occurs late after repair of a congenital heart defect, the atrial flutter isthmus should be evaluated. These data support the theory that some form of conduction block between the vena cava is essential for the establishment of a stable substrate for the atrial flutter reentrant circuit.
在先天性心脏手术幸存者中,常发生房内折返性心动过速(IART)。既往报告强调心房切开瘢痕是折返环可能围绕其旋转的中心屏障,但未系统评估此类患者的心房扑动峡部。我们试图确定心房扑动峡部在一组先天性心脏病术后患者支持IART中的作用。
19例IART术后患者接受了电生理研究,对心房扑动峡部进行拖带标测以确定起搏后间期。在确定的峡部进行射频消融,试图形成完整的阻滞线。在19例患者中识别出21次IART,平均心动过速周期长度为293±73毫秒。21次IART中有15次(71.4%)心房扑动峡部是折返环的一部分。在其余21次中的6次,消融靶点位于心房切口或缝线附近部位。21次IART中有19次(90.4%)消融成功,在心房扑动峡部的15例中有14例(93.3%)成功。
在我们的大多数术后患者中,心房扑动峡部是折返环的一部分。心房扑动峡部易被消融这一事实表明,每当先天性心脏缺陷修复后晚期发生IART时,应评估心房扑动峡部。这些数据支持这样一种理论,即腔静脉之间某种形式的传导阻滞对于建立心房扑动折返环的稳定基质至关重要。