Chou Ching-Yao, Chung Fa-Po, Chang Hung-Yu, Lin Yenn-Jiang, Lo Li-Wei, Hu Yu-Feng, Chao Tze-Fan, Liao Jo-Nan, Tuan Ta-Chuan, Lin Chin-Yu, Chang Ting-Yung, Liu Chih-Min, Wu Cheng-I, Huang Sung-Hao, Chen Chun-Chao, Cheng Wen-Han, Liu Shin-Huei, Lugtu Isaiah Carlos, Jain Ankit, Feng An-Ning, Chang Shih-Lin, Chen Shih-Ann
Heart Rhythm Center and Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Division of Cardiology, Medical Center, Shin Kong Wu Ho Su Memorial Hospital, Taipei, Taiwan.
Front Cardiovasc Med. 2021 Sep 23;8:741377. doi: 10.3389/fcvm.2021.741377. eCollection 2021.
Surgical scars cause an intra-atrial conduction delay and anatomical obstacles that facilitate the perpetuation of atrial flutter (AFL). This study aimed to investigate the outcome and predictor of recurrent atrial tachyarrhythmia after catheter ablation in patients with prior cardiac surgery for valvular heart disease (VHD) who presented with AFL. Seventy-two patients with prior cardiac surgery for VHD who underwent AFL ablation were included. The patients were categorized into a typical AFL group ( = 45) and an atypical AFL group ( = 27). The endpoint was the recurrence of atrial tachyarrhythmia during follow-up. A multivariate analysis was performed to determine the predictor of recurrence. No significant difference was found in the recurrence rate of atrial tachyarrhythmia between the two groups. Patients with concomitant atrial fibrillation (AF) had a higher recurrence of typical AFL compared with those without AF (13 vs. 0%, = 0.012). In subgroup analysis, typical AFL patients with concomitant AF had a higher incidence of recurrent atrial tachyarrhythmia than those without it (53 vs. 14%, = 0.006). Regarding patients without AF, the typical AFL group had a lower recurrence rate of atrial tachyarrhythmia than the atypical AFL group (14 vs. 40%, = 0.043). Multivariate analysis showed that chronic kidney disease (CKD) and left atrial diameter (LAD) were independent predictors of recurrence. In our study cohort, concomitant AF was associated with recurrence of atrial tachyarrhythmia. CKD and LAD independently predicted recurrence after AFL ablation in patients who have undergone cardiac surgery for VHD.
手术疤痕会导致心房内传导延迟和解剖学障碍,从而促使心房扑动(AFL)持续存在。本研究旨在调查患有瓣膜性心脏病(VHD)且曾接受心脏手术并出现AFL的患者在导管消融术后复发性房性快速心律失常的结局及预测因素。纳入了72例曾因VHD接受心脏手术并进行AFL消融的患者。这些患者被分为典型AFL组(n = 45)和非典型AFL组(n = 27)。终点指标为随访期间房性快速心律失常的复发情况。进行多变量分析以确定复发的预测因素。两组房性快速心律失常的复发率无显著差异。伴有心房颤动(AF)的患者与无AF的患者相比,典型AFL的复发率更高(13% 对0%,P = 0.012)。在亚组分析中,伴有AF的典型AFL患者房性快速心律失常复发的发生率高于无AF的患者(53% 对14%,P = 0.006)。对于无AF的患者,典型AFL组房性快速心律失常的复发率低于非典型AFL组(14% 对40%,P = 0.043)。多变量分析显示,慢性肾脏病(CKD)和左心房直径(LAD)是复发的独立预测因素。在我们的研究队列中,伴有AF与房性快速心律失常的复发相关。CKD和LAD独立预测了因VHD接受心脏手术的患者在AFL消融术后的复发情况。