Fassler C, Lanco S, Denis A, Penniello M J, Duncombe-Poulet C, Guillois B
Service de pédiatrie B, hôpital Clemenceau, France.
Arch Pediatr. 2000 Aug;7(8):840-3. doi: 10.1016/S0929-693X(00)80193-1.
Although myiasis or hypodermiasis is a parasitic disease that theoretically has practically been eradicated, a new case has recently been reported in Lower Normandy, in a bovine husbandry region.
A seven-year-old-girl was hospitalized in November 1998 for an edema of variable size on the right eyelid, which was not painful and non-inflammatory, with accompanying ptosis. A number of subcutaneous nodules were found on the forehead above the right eye socket. The right eye itself was unaffected. The symptoms had evolved over a ten-day period. Further examination did not detect any sign of eosinophilia, and the hypodermiasis and toxocariasis serologies were negative. The clinical evolution was characterized by the regression and reappearance of the edema on several occasions, after which the edematous mass became progressively larger, more swollen and painful, so that it was no longer possible to open the eye. The subcutaneous nodules partially disappeared when the edema increased in size. Six weeks after the onset of clinical signs, eosinophilia was observed and the hypodermiasis serology was positive. Due to the limitation of the visual field as a result of the edema, a short-term steroid treatment (seven days) was orally administered. The patient recovered, and no further edematous signs were noted. However, contrary to what had been reported in the literature, the larvae did not appear on the surface of the skin.
In conclusion, in bovine husbandry regions the diagnosis of hypodermiasis should always be kept in mind in the event of clinical signs indicative of larval migration, even in the initial absence of eosinophilia, and even with an initially negative hypodermiasis serology. This disease should soon be eradicated, as regional bovine treatment programs have been set up to systematically treat the cattle and eliminate the larvae.
虽然蝇蛆病或皮下蝇蛆病是一种理论上已几乎被根除的寄生虫病,但最近在下诺曼底的一个养牛区报告了一例新病例。
一名七岁女孩于1998年11月因右眼睑出现大小不一的水肿而住院,该水肿无痛且无炎症,伴有上睑下垂。在右眼窝上方的额头上发现了一些皮下结节。右眼本身未受影响。症状在十天内逐渐发展。进一步检查未发现嗜酸性粒细胞增多的迹象,皮下蝇蛆病和弓蛔虫病血清学检查均为阴性。临床病程的特点是水肿多次消退和再现,之后水肿肿块逐渐变大、肿胀加剧且疼痛,导致无法睁开眼睛。当水肿增大时,皮下结节部分消失。临床症状出现六周后,观察到嗜酸性粒细胞增多,皮下蝇蛆病血清学检查呈阳性。由于水肿导致视野受限,口服了短期类固醇治疗(七天)。患者康复,未再出现水肿迹象。然而,与文献报道不同的是,幼虫未出现在皮肤表面。
总之,在养牛区,如果出现提示幼虫移行的临床症状,即使最初没有嗜酸性粒细胞增多,即使皮下蝇蛆病血清学检查最初为阴性,也应始终考虑皮下蝇蛆病的诊断。由于已经制定了区域养牛治疗方案来系统治疗牛群并消灭幼虫,这种疾病应很快被根除。