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[肠道再循环在实验性短肠综合征治疗中的应用(作者译)]

[Intestinal recirculation in the management of experimental short bowel syndrome (author's transl)].

作者信息

López Pérez G A, Gaztambide Casellas J, Quadri Duque A

出版信息

An Esp Pediatr. 1975 May-Jun;8(3):243-8.

PMID:1098536
Abstract

A short bowel syndrome was produced in 33 mongrel puppies less than one month of age, by resecting 80% of the small bowel. An end-to-end anastomosis was performed in 14 dogs (Group A). Sixteen dogs were reanastomosed by performing an isoperistaltic circular intestinal loop, modified from Tanner and Mackby (Group B). Three dogs had a circular loop performed using Mackby method, but this technique was abandoned because of intraluminal stasis. Long term survival on 18 dogs was 12,5% for Group A and 57% for Group B. Weight gain on the survivors was over 25% higher in Group B. Intestinal transit time was abnormally short only in Group A. The loop procedure seems worthy of further clinical trial.

摘要

通过切除80%的小肠,在33只小于1月龄的杂种幼犬中制造短肠综合征。14只狗进行了端端吻合术(A组)。16只狗通过进行等蠕动环形肠袢吻合术重新吻合,该术式由Tanner和Mackby改良而来(B组)。3只狗采用Mackby方法进行环形肠袢吻合,但由于腔内淤滞,该技术被放弃。A组18只狗的长期存活率为12.5%,B组为57%。B组存活者的体重增加超过A组25%以上。仅A组的肠道转运时间异常缩短。肠袢手术似乎值得进一步进行临床试验。

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