A fraction isolated from Ehrlich ascites carcinoma as an antitumor and differentiating agent against human leukemic cell ML-2.
作者信息
Sur P, Nandi N, Ghosh P, Ghosh N C
机构信息
Department of Pharmacology and Experimental Therapeutics, Indian Institute of Chemical Biology, Jadavpur University, Calcutta.
出版信息
Neoplasma. 2000;47(2):114-7.
PMID:10985477
Abstract
Lipopolysaccharide fraction isolated from Ehrlich ascites carcinoma (E-LPS) was investigated as an antitumor agent against human leukemia cell ML-2. Marked cell growth inhibition was observed with ML-2 cell accompanied by inhibition of DNA synthesis and perturbation of cell cycle. Induction of differentiation in treated ML-2 cells was observed as indicated by morphological maturation, NBT reducing activity and indirect immunofluorescence.
摘要
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