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[不同浓度含抑素制剂作用下艾氏腹水癌细胞培养物中DNA合成水平的变化]

[Changes in the level of DNA synthesis in a culture of Ehrlich ascites tumor cells under the action of different concentrations of a chalone-containing preparation].

作者信息

Gembitskiĭ D S, Antokhin A I, Romanov Iu A, Popova N Ia

出版信息

Biull Eksp Biol Med. 1992 Dec;114(12):651-2.

PMID:1292703
Abstract

The study was made of the effect of various concentrations of chalone-containing preparation from ascitic Ehrlich tumor on DNA synthesis in the tumor. The preparation was shown to suppress DNA synthesis in dose-dependent manner. The dose dependence was characterized by the effect of saturation which is likely to reflect binding of chalone molecules with specific cell receptors.

摘要

研究了来自腹水型艾氏瘤的含抑瘤素制剂的不同浓度对肿瘤中DNA合成的影响。结果表明该制剂以剂量依赖性方式抑制DNA合成。剂量依赖性的特征在于饱和效应，这可能反映了抑瘤素分子与特定细胞受体的结合。

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1
[Changes in the level of DNA synthesis in a culture of Ehrlich ascites tumor cells under the action of different concentrations of a chalone-containing preparation].[不同浓度含抑素制剂作用下艾氏腹水癌细胞培养物中DNA合成水平的变化]
Biull Eksp Biol Med. 1992 Dec;114(12):651-2.
2
[Effect of different doses of a chalone-containing alcohol precipitate of Ehrlich ascitic tumor on the mitotic activity and DNA synthesis in this tumor].[不同剂量艾氏腹水瘤含抑素乙醇沉淀物对该肿瘤有丝分裂活性及DNA合成的影响]
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A fraction isolated from Ehrlich ascites carcinoma as an antitumor and differentiating agent against human leukemic cell ML-2.
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[Relation between the mitosis-inhibitory activity of a chalone preparation of Ehrlich ascites tumor and its diurnal secretion].[艾氏腹水瘤查隆制剂的有丝分裂抑制活性与其昼夜分泌之间的关系]
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