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高流行地区(亚马逊地区)家庭内接触者麻风病的早期诊断与治疗

Early diagnosis and treatment of leprosy in intradomiciliary contacts in a high prevalence area: Amazon region.

作者信息

Pennini S N, Pedrosa L, Rebello P F

机构信息

Instituto De Dermatologia Tropical e Venereologia Alfredo Da Matta, Manaus, Amazonas, Brazil.

出版信息

Indian J Lepr. 1998;70 Suppl:73S-77S.

Abstract

The importance of dermato-neurological examination of intradomiciliary contacts is well known as an important secondary preventive measure in leprosy control, due to the fact that it allows early diagnosis and treatment. This is an intervention trial in an area of high leprosy prevalence (Manaus/Brazil) where the proportion of contacts examined is low. The aim of the study is to assess whether a simple educational session conducted among patients increases contacts examination and leads to early case detection. The intervention group had examined more contacts (p < 0.05) but, paradoxically, presented fewer new cases than the control group. The authors discuss the probable causes for this unexpected outcome, the advantages of the intervention and other related issues.

摘要

由于对家庭内接触者进行皮肤神经学检查能够实现早期诊断和治疗,所以它作为麻风病控制中的一项重要二级预防措施,其重要性是众所周知的。这是在麻风病高流行地区(巴西马瑙斯)开展的一项干预试验,该地区接受检查的接触者比例较低。本研究的目的是评估在患者中开展一次简单的教育活动是否会增加对接触者的检查,并能实现早期病例发现。干预组检查的接触者更多(p < 0.05),但自相矛盾的是,与对照组相比,新病例却更少。作者讨论了这一意外结果的可能原因、干预措施的优势以及其他相关问题。

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