Nardi P, Scafuri A, Bertoldo F, el Fakhri F, De Matteis G M, Forlani S, Chiariello L
Cattedra di Cardiochirurgia, Università degli Studi Tor Vergata, Roma.
Ital Heart J Suppl. 2000 Aug;1(8):1059-62.
Atrial septal aneurysm can be associated with other cardiovascular diseases such as atrial septal defect, patent ductus arteriosus, pulmonary hypertension and cerebrovascular events (transient ischemic attack or stroke). The introduction of transthoracic and more recently transesophageal echocardiography allowed for a more frequent observation of this pathology and also suggested that atrial septal aneurysm is a risk factor for cerebral ischemia. However, the pathophysiological pathway is still unclear. In January 1997 a 33-year-old man was admitted to our hospital because of atrial septal aneurysm and a previous cerebrovascular event. Magnetic resonance imaging revealed a cerebrovascular malformation and transesophageal echocardiography confirmed the presence of atrial septal aneurysm. We hypothesize that a common etiopathogenetic pathway may cause both the cardiac and cerebrovascular anomaly and that the latter may be responsible alone for cerebral ischemic events; thus in the presence of an atrial septal aneurysm associated with a cerebrovascular malformation, a conservative medical approach may be the treatment of choice.
房间隔瘤可与其他心血管疾病相关，如房间隔缺损、动脉导管未闭、肺动脉高压和脑血管事件（短暂性脑缺血发作或中风）。经胸超声心动图以及最近的经食管超声心动图的引入，使得这种病变的观察更为频繁，也提示房间隔瘤是脑缺血的一个危险因素。然而，其病理生理途径仍不清楚。1997年1月，一名33岁男性因房间隔瘤和既往脑血管事件入住我院。磁共振成像显示脑血管畸形，经食管超声心动图证实存在房间隔瘤。我们推测，一个共同的病因发病途径可能导致心脏和脑血管异常，且后者可能单独导致脑缺血事件；因此，在存在与脑血管畸形相关的房间隔瘤的情况下，保守的药物治疗可能是首选治疗方法。
