Pan W B, Chang F R, Wu Y C
Department of Applied Chemistry, Fooyin Institute of Technology, Kaohsiung County, Taiwan.
Chem Pharm Bull (Tokyo). 2000 Sep;48(9):1350-3. doi: 10.1248/cpb.48.1350.
Chemical examination of the underground parts of Tupistra chinensis led to the isolation of two new 5beta-spirostane type steroidal sapogenins, tupichigenin B (1) and C (2), together with two known steroidal sapogenins, ranmogenin A (3) and delta25(27)-pentrogenin (4). The structures of 1 and 2 were established as spirost-25(27)-ene-1beta,3beta,4beta,5beta,6b eta-pentaol and 1beta,2beta,3beta,4beta,5beta-pentahydroxyspi rost-25(27)-en-6-one, respectively, on the basis of detailed analysis of their physical and spectral data.
对开口箭地下部分进行化学研究，从中分离得到两个新的5β-螺旋甾烷型甾体皂苷元，开口箭皂苷元B（1）和C（2），以及两个已知的甾体皂苷元，知母皂苷元A（3）和Δ25(27)-戊热皂苷元（4）。通过对化合物1和2的物理数据和光谱数据进行详细分析，分别确定其结构为螺旋甾-25(27)-烯-1β,3β,4β,5β,6β-五醇和1β,2β,3β,4β,5β-五羟基螺旋甾-25(27)-烯-6-酮。
