Michaelides E M, Sismanis A, Sugerman H J, Felton W L
Department of Otolaryngology/Head Neck Surgery, Medical College of Virginia of Virginia Commonwealth University, Richmond 23298, USA.
Am J Otol. 2000 Sep;21(5):682-5.
Morbid obesity is increasing in the United States population. Morbidly obese patients may have disabling pulsatile tinnitus (PT) secondary to pseudotumor cerebri syndrome and often seek treatment from otolaryngologists because of this symptom.
To determine the effectiveness of weight reduction surgery (WRS) for relief of PT in patients with morbid obesity.
Retrospective study of morbidly obese patients with associated PT.
Academic tertiary referral center.
Sixteen women with morbid obesity and associated PT who underwent WRS.
Median age was 34 years (range 24-45 years). Average preoperative body mass index was 45 kg/m2 (range 33-70 kg/m2). Average weight loss was 45+/-17 kg (range 25-99 kg). Average postoperative weight was 75+/-14 kg (range 57-105 kg). The average preoperative cerebrospinal fluid pressure was 344+/-103 mm H2O (range 220-520 mm H2O). Postoperative measurements of cerebrospinal fluid, obtained on 4 patients, revealed an average decrease in pressure of 198 mm H2O (range 120-400 mm H2O). Thirteen patients experienced complete resolution of their PT (81%). Three patients continued to have PT despite significant weight reduction.
Weight reduction surgery was effective in relieving PT in morbidly obese patients with associated pseudotumor cerebri syndrome and should be considered when conservative management has failed.
在美国人群中,病态肥胖的情况正在增加。病态肥胖患者可能因假性脑瘤综合征继发致残性搏动性耳鸣(PT),并且常因此症状寻求耳鼻喉科医生的治疗。
确定减重手术(WRS)对缓解病态肥胖患者PT的有效性。
对伴有PT的病态肥胖患者进行回顾性研究。
学术性三级转诊中心。
16例接受WRS的病态肥胖且伴有PT的女性。
中位年龄为34岁(范围24 - 45岁)。术前平均体重指数为45kg/m²(范围33 - 70kg/m²)。平均体重减轻45±17kg(范围25 - 99kg)。术后平均体重为75±14kg(范围57 - 105kg)。术前平均脑脊液压力为344±103mm H₂O(范围220 - 520mm H₂O)。4例患者术后脑脊液测量显示压力平均下降198mm H₂O(范围120 - 400mm H₂O)。13例患者的PT完全缓解(81%)。3例患者尽管体重显著减轻仍持续存在PT。
减重手术对缓解伴有假性脑瘤综合征的病态肥胖患者的PT有效,在保守治疗失败时应予以考虑。