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多奈哌齐治疗快速眼动睡眠行为障碍:三例报告

Treatment of REM sleep behavior disorder with donepezil: a report of three cases.

作者信息

Ringman J M, Simmons J H

机构信息

Department of Neurology, University of California, Irvine Medical Center, Orange, CA, USA.

出版信息

Neurology. 2000 Sep 26;55(6):870-1. doi: 10.1212/wnl.55.6.870.

DOI:10.1212/wnl.55.6.870
PMID:10994012
Abstract

Three patients with REM behavior disorder whose nocturnal symptoms were markedly improved by treatment with the acetylcholinesterase inhibitor donepezil are reported. Donepezil may have a role in the treatment of REM behavior disorder, possibly through its actions on cholinergic pathways in the brainstem.

摘要

报告了3例快速眼动睡眠行为障碍患者,其夜间症状通过乙酰胆碱酯酶抑制剂多奈哌齐治疗后明显改善。多奈哌齐可能在快速眼动睡眠行为障碍的治疗中发挥作用,可能是通过其对脑干胆碱能通路的作用。

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