Ringman J M, Simmons J H
Department of Neurology, University of California, Irvine Medical Center, Orange, CA, USA.
Neurology. 2000 Sep 26;55(6):870-1. doi: 10.1212/wnl.55.6.870.
Three patients with REM behavior disorder whose nocturnal symptoms were markedly improved by treatment with the acetylcholinesterase inhibitor donepezil are reported. Donepezil may have a role in the treatment of REM behavior disorder, possibly through its actions on cholinergic pathways in the brainstem.
报告了3例快速眼动睡眠行为障碍患者,其夜间症状通过乙酰胆碱酯酶抑制剂多奈哌齐治疗后明显改善。多奈哌齐可能在快速眼动睡眠行为障碍的治疗中发挥作用,可能是通过其对脑干胆碱能通路的作用。