Zucker B A, Müller W
Institut für Tier- und Umwelthygiene der Freien Universität Berlin.
Berl Munch Tierarztl Wochenschr. 2000 Jul-Aug;113(7-8):279-83.
The relationship between inhalable endotoxin, inhalable dust and airborne bacteria was studied in a hen house. Neither the concentration of inhalable dust nor the concentration of airborne bacteria are suitable to reflect the concentration of airborne endotoxin. Furthermore it was found that the endotoxic activity can persist over a long period of time in dust samples. Therefore an accumulation of endotoxin in different environments is possible. Airborne endotoxin seems to be a suitable marker to characterize exposure to airborne organic dust, since this toxin is responsible for different respiratory diseases (e.g. toxic pneumonitis, airway obstructions) and the toxic activity of endotoxin in dust samples is known to persist for a long time.
在一个鸡舍中研究了可吸入内毒素、可吸入粉尘与空气中细菌之间的关系。可吸入粉尘浓度和空气中细菌浓度均不适于反映空气中内毒素的浓度。此外,还发现内毒素活性在粉尘样本中可长期持续存在。因此,内毒素在不同环境中有可能会累积。空气中的内毒素似乎是表征接触空气中有机粉尘的一个合适指标,因为这种毒素会引发不同的呼吸道疾病(如中毒性肺炎、气道阻塞),而且已知粉尘样本中内毒素的毒性活性会长期持续存在。