Inoue S, Tanaka K
Department of Pathology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Otolaryngol Head Neck Surg. 1982 Nov-Dec;90(6):801-7. doi: 10.1177/019459988209000622.
Fibrinolytic activity in the inner ear of human beings and guinea pigs was assayed qualitatively and quantitatively. It was found that fibrinolytic activity of the stria vascularis was caused by a conversion of plasminogen to plasmin by tissue plasminogen activator and was moderate in degree compared with that of other organs in both species. In human beings, endolymph showed higher plasminogen activator activity than that of CSF. Plasminogen activator activity was not detected in either endolymph or perilymph of guinea pigs. Thrombin infusion diminished plasminogen activator activity in the stria vascularis of guinea pigs.
对人类和豚鼠内耳的纤溶活性进行了定性和定量分析。结果发现，血管纹的纤溶活性是由组织纤溶酶原激活物将纤溶酶原转化为纤溶酶所致，与两个物种的其他器官相比，其程度适中。在人类中，内淋巴的纤溶酶原激活物活性高于脑脊液。在豚鼠的内淋巴或外淋巴中均未检测到纤溶酶原激活物活性。注入凝血酶可降低豚鼠血管纹中的纤溶酶原激活物活性。
