Fria T J, Saad M M, Doyle W J, Cantekin E I
Department of Otolaryngology, University of Pittsburgh School of Medicine, USA.
Otolaryngol Head Neck Surg. 1982 Nov-Dec;90(6):824-30. doi: 10.1177/019459988209000626.
Auditory brain stem response (ABR) tests were conducted on 17 anesthetized juvenile rhesus monkeys. Recordings were obtained for 13 control ears without otitis media with effusion (OME) and seven experimental ears with OME. The results demonstrated an increase in response latencies for the experimental ears with OME at each of four stimulus presentation levels (80, 60, 40, and 20 dB hearing level). Interwave latencies were the same for both groups of ears. The results suggest an average 25-dB peripheral loss of predominantly middle ear origin associated with OME. The ABR appeared to be a viable technique for documenting auditory impairment associated with OME in this nonhuman primate model.
对17只麻醉状态下的幼年恒河猴进行了听觉脑干反应（ABR）测试。对13只无中耳积液（OME）的对照耳和7只患有OME的实验耳进行了记录。结果表明，在四个刺激呈现水平（80、60、40和20分贝听力水平）下，患有OME的实验耳的反应潜伏期均增加。两组耳朵的波间期相同。结果表明，与OME相关的平均25分贝外周听力损失主要起源于中耳。在这个非人灵长类动物模型中，ABR似乎是一种记录与OME相关听觉损伤的可行技术。
