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The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.
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Role of spindle assembly checkpoint proteins in gametogenesis and embryogenesis.
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MARVEL: an integrated alternative splicing analysis platform for single-cell RNA sequencing data.
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DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism.
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Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2.
Cell. 2000 Jun 9;101(6):635-45. doi: 10.1016/s0092-8674(00)80875-2.
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Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function.
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Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice.
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Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC.
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Retention of the BUB3 checkpoint protein on lagging chromosomes.
Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8493-8. doi: 10.1073/pnas.96.15.8493.
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Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila.
J Cell Biol. 1999 Jul 12;146(1):13-28. doi: 10.1083/jcb.146.1.13.
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Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice.
Hum Mol Genet. 1999 Jul;8(7):1145-55. doi: 10.1093/hmg/8.7.1145.
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The spindle checkpoint.
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Kinetochores and the checkpoint mechanism that monitors for defects in the chromosome segregation machinery.
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Localization of the Drosophila checkpoint control protein Bub3 to the kinetochore requires Bub1 but not Zw10 or Rod.
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