Cantallops I, Cline H T
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Curr Biol. 2000 Sep 7;10(17):R620-3. doi: 10.1016/s0960-9822(00)00663-1.
Neuroligin and neurexin form an intercellular adhesion complex sufficient to trigger formation of functional presynaptic elements in vitro. This single molecular interaction appears to initiate clustering of synaptic vesicles, assembly of vesicle-release machinery and morphological changes at the presynaptic membrane.
神经连接蛋白和神经突触素形成一种细胞间黏附复合物，足以在体外触发功能性突触前元件的形成。这种单一的分子相互作用似乎会引发突触小泡的聚集、囊泡释放机制的组装以及突触前膜的形态变化。
