Gibson T, Dilke T F, Grahame R
Rheumatol Rehabil. 1975 Aug;14(3):186-90. doi: 10.1093/rheumatology/14.3.186.
Ninety-three patients with lumbar disc prolapse of less than six months duration were treated with Chymoral or an identical placebo in a double-blind study. Those patients given Chymoral exhibited significantly greater improvement of straight-leg raising and received significantly fewer analgesics. However, no difference was apparent with regard to other parameters, and similar numbers from both groups required further therapy. Over-all, the value of Chymoral in the treatment of lumbar disc prolapse seemed little better than a placebo.
在一项双盲研究中，93例病程少于6个月的腰椎间盘突出症患者接受了糜蛋白酶或相同安慰剂治疗。接受糜蛋白酶治疗的患者直腿抬高改善情况显著更好，且服用的镇痛药明显更少。然而，在其他参数方面没有明显差异，两组中需要进一步治疗的人数相近。总体而言，糜蛋白酶在治疗腰椎间盘突出症方面的价值似乎并不比安慰剂好多少。
