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[根据不同组别和科学协会对2型糖尿病患者高胆固醇血症的控制程度及成本分析]

[Cost analysis and degree of hypercholesterolemia control in type 2 diabetic patients according to different groups and scientific societies].

作者信息

Narejos S, Espinàs J, Rodríguez A, Salla R M, Blay C, Puente A, Cantero M, Alsina J, López M C

机构信息

ABS Sta, Eugènia de Berga, Unidad Docente de MFyC Centro, Barcelona.

出版信息

Aten Primaria. 2000 Jul-Aug;26(3):145-50. doi: 10.1016/s0212-6567(00)78631-8.

Abstract

OBJECTIVES

To analyse the cost and describe the degree of control of the hypercholesterolaemia of type-2 diabetic (DM2) patients according to different groups and scientific societies.

DESIGN

Retrospective cross-sectional study.

SETTING

Rural health area.

PATIENTS

All DM2 patients monitored in the health area (n = 338).

MEASUREMENTS AND MAIN RESULTS

Gathering of data on clinical histories, determination of cardiovascular risk, LDL-C concentration and total/HDL cholesterol index. DM2 prevalence was 3.08%; annual incidence, 2.55/1000; 45.2% presented hypercholesterolaemia; 16.9% received lipid-lowering treatment; and 20.1% (n = 68) had DM2 with cardiovascular disease. According to the criteria of the GEDAPS-99, European Consensus-98 (Framingham table), Sheffield Group (objectives of the European Consensus-98) and PAPPS-99 for primary prevention, 59.3%, 58.4%, 24.5% and 17.7%, respectively, of hypercholesterolaemic patients were poorly controlled. The percentages of hypercholesterolaemic patients who in each case should receive treatment were: 64.9%, 66.1%, 36.4% and 29.6%. Expenditure in thousands of pesetas every 28 days to achieve proper control of these patients was 282, 423, 274 and 117. The criteria on secondary prevention of the GEDAPS-99 and European Consensus-98 gave figures of 81% and 72.4%, respectively, of poor control of Hypercholesterolaemia. 82.7% and 77.5% of these patients should receive treatment. Expenditure in thousands of pesetas every 28 days to achieve proper control of these patients was 342 and 210.

CONCLUSIONS

The degree of control and the costs of hypercholesterolaemia in both primary and secondary prevention vary enormously, depending on the criterion used by the group or scientific society.

摘要

目的

根据不同组别和科学协会分析2型糖尿病(DM2)患者高胆固醇血症的成本并描述其控制程度。

设计

回顾性横断面研究。

地点

农村卫生区。

患者

在该卫生区接受监测的所有DM2患者(n = 338)。

测量与主要结果

收集临床病史数据,确定心血管风险、低密度脂蛋白胆固醇(LDL-C)浓度以及总胆固醇/高密度脂蛋白胆固醇指数。DM2患病率为3.08%;年发病率为2.55/1000;45.2%的患者出现高胆固醇血症;16.9%的患者接受降脂治疗;20.1%(n = 68)的患者患有DM2合并心血管疾病。根据GEDAPS - 99、欧洲共识 - 98(弗明翰表)、谢菲尔德小组(欧洲共识 - 98目标)和PAPPS - 99的一级预防标准,分别有59.3%、58.4%、24.5%和17.7%的高胆固醇血症患者控制不佳。每种情况下应接受治疗的高胆固醇血症患者百分比分别为:64.9%、66.1%、36.4%和29.6%。每28天实现对这些患者的适当控制所需的支出(以千比塞塔计)分别为282、423、274和117。GEDAPS - 99和欧洲共识 - 98的二级预防标准显示,高胆固醇血症控制不佳的比例分别为81%和72.4%。这些患者中82.7%和77.5%应接受治疗。每28天实现对这些患者的适当控制所需的支出(以千比塞塔计)分别为342和210。

结论

一级和二级预防中高胆固醇血症的控制程度和成本差异巨大,这取决于所采用的组别或科学协会的标准。

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