Wali Y A, al-Lamki Z, Soliman H, al-Okbi H
Department of Child Health, Sultan Qaboos University, Sultanate of Oman.
J Trop Pediatr. 2000 Aug;46(4):246-8. doi: 10.1093/tropej/46.4.246.
Cerebrovascular accident is one of the most serious complications of sickle cell anemia. The specific factors that predispose patients with sickle cell anemia to stroke are increased disease severity, higher baseline white blood cell count and lower baseline hematocrits. Likewise the presence of a co-existent alpha thalassemia trait and/or high fetal hemoglobin (HbF%) may reduce the risk. We report a child with sickle cell anemia and marked adenotonsillar hypertrophy resulting in obstructive sleep apnea syndrome. There was no other known risk factor for developing cerebrovascular accident in this child during her hospitalization for adenotonsillectomy.
脑血管意外是镰状细胞贫血最严重的并发症之一。使镰状细胞贫血患者易患中风的具体因素包括疾病严重程度增加、基线白细胞计数较高和基线血细胞比容较低。同样，共存的α地中海贫血特征和/或高胎儿血红蛋白（HbF%）的存在可能会降低风险。我们报告一名患有镰状细胞贫血且伴有明显腺样体扁桃体肥大导致阻塞性睡眠呼吸暂停综合征的儿童。在该儿童因腺样体扁桃体切除术住院期间，没有其他已知的发生脑血管意外的风险因素。
