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厚皮马拉色菌在犬外耳炎中的作用:咪康唑治疗的评估

The role of Pityrosporum pachydermatis in otitis externa of dogs: evaluation of a treatment with miconazole.

作者信息

Gedek B, Brutzel K, Gerlach R, Netzer F, Rocken H, Unger H, Symoens J

出版信息

Vet Rec. 1979 Feb 17;104(7):138-40. doi: 10.1136/vr.104.7.138.

Abstract

The bacterial and mycotic flora were assessed in 158 ears of dogs with otitis externa and in 101 ears of healthy control dogs. Pityrosporum pachydermatis occurred in 57 per cent of ears with otitis externa and in 17 per cent of clinically healthy ears. Staphylococci and Pseudomonas aeruginosa were the predominant bacteria in otitic ears, micrococci and Bacillus spp were the most frequent isolates from clinically healthy ears. P pachydermatis, Ps aeruginosa and Candida tropicalis occurred in monoculture in a significant number of mainly chronic cases of otitis externa. A combination preparation, containing miconazole, polymyzin B and prednisolone, was highly effective in controlling the clinical signs of otitis externa and eliminating flora from the affected ears. The data presented suggest that yeasts, and especially P pachydermatis, may be significant pathogens in otitis externa and that antimycotic treatment is an essential part of the treatment of otitis externa in dogs.

摘要

对158只患有外耳炎的犬耳和101只健康对照犬耳的细菌和真菌菌群进行了评估。厚皮马拉色菌在57%的外耳炎犬耳中出现,在17%的临床健康犬耳中出现。葡萄球菌和铜绿假单胞菌是患耳中的主要细菌,微球菌和芽孢杆菌属是临床健康犬耳中最常见的分离菌。厚皮马拉色菌、铜绿假单胞菌和热带念珠菌在大量主要为慢性外耳炎病例中呈单一培养出现。一种含有咪康唑、多粘菌素B和泼尼松龙的复方制剂在控制外耳炎的临床症状和清除患耳中的菌群方面非常有效。所呈现的数据表明,酵母菌,尤其是厚皮马拉色菌,可能是外耳炎的重要病原体,抗真菌治疗是犬外耳炎治疗的重要组成部分。

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