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精油对犬猫外耳炎致病病原体的抗菌和抗真菌活性

Antibacterial and Antifungal Activity of Essential Oils against Pathogens Responsible for Otitis Externa in Dogs and Cats.

作者信息

Ebani Valentina V, Nardoni Simona, Bertelloni Fabrizio, Najar Basma, Pistelli Luisa, Mancianti Francesca

机构信息

Department of Veterinary Science, University of Pisa, viale delle Piagge 2, 56124 Pisa, Italy.

Centro Interdipartimentale di Ricerca "Nutraceutica e Alimentazione per la Salute", University of Pisa, via del Borghetto 80, 56124 Pisa, Italy.

出版信息

Medicines (Basel). 2017 Apr 21;4(2):21. doi: 10.3390/medicines4020021.

Abstract

Essential oils (EOs) are recommended by some veterinarians to treat otitis externa in pets, but data about their efficacy in scientific literature are very scant. Nine commercial EOs, from roman chamomile ( L.), star anise (), lavender (), litsea ( (Lour.) Pers.), basil ( L.), oregano ( L. subsp. ), rosemary ( L.), clary sage ( L.), and thyme ( L.) were tested against bacterial and fungal pathogens previously isolated from dogs and cats with otitis externa. In particular, the analyses were carried out against , sp., and sp. and showed superior antibacterial activity, even if not against all the strains. sp., , and were insensitive to most Eos, while other yeasts and molds showed different degrees of sensitivity. In particular, most fungi were inhibited by and . The obtained results suggest that some EOs could be included in treatment as an alternative therapeutic option in bacterial otitis complicated by fungi, in association with conventional drugs.

摘要

一些兽医推荐使用香精油(EOs)治疗宠物外耳炎,但科学文献中关于其疗效的数据非常稀少。对九种市售香精油进行了测试,它们分别来自罗马洋甘菊(L.)、八角茴香()、薰衣草()、山鸡椒((Lour.)Pers.)、罗勒(L.)、牛至(L. subsp.)、迷迭香(L.)、鼠尾草(L.)和百里香(L.),测试对象为先前从患有外耳炎的犬猫中分离出的细菌和真菌病原体。特别是,针对、sp.、sp.进行了分析。和表现出较强的抗菌活性,即使并非对所有菌株都有效。sp.、和对大多数香精油不敏感,而其他酵母和霉菌则表现出不同程度的敏感性。特别是,大多数真菌受到和的抑制。所得结果表明,在与传统药物联合使用时,一些香精油可作为真菌并发的细菌性外耳炎的替代治疗选择纳入治疗方案。

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