Nikolajsen L, Staehelin Jensen T
Department of Neurology and Danish Pain Research Center, University of Aarhus, Aarhus Kommunehospital, Building 1 C, Nørrebrogade 44, Aarhus C, DK 8000, Denmark.
Curr Rev Pain. 2000;4(2):166-70. doi: 10.1007/s11916-000-0052-0.
Phantom pain is experienced by 60% to 80% of patients following limb amputation but is only severe in about 5% to 10% of cases. The mechanisms underlying pain in amputees are not fully understood, but factors in both the peripheral and central nervous system play a role. Treatment of phantom pain is not successful; a recent study on prevention of phantom pain showed negative results. The future may reveal new specific drugs for treatment.
60%至80%的截肢患者会经历幻肢痛,但只有约5%至10%的病例疼痛严重。截肢者疼痛的潜在机制尚未完全了解,但外周和中枢神经系统的因素都起作用。幻肢痛的治疗并不成功;最近一项关于预防幻肢痛的研究显示出负面结果。未来可能会出现新的特效治疗药物。