Litvak D, Kirsner R S, Pakdaman N N, Federman D G
Department of Medicine, Yale University School of Medicine, New Haven, Conn, USA.
South Med J. 2000 Sep;93(9):923-5.
Pyoderma gangrenosum (PG) is a painful, often rapidly progressive, ulcerating skin disorder frequently associated with systemic diseases. We report the case of a patient with PG and an anemia. A bone marrow biopsy showed changes consistent with one of the myelodysplastic syndromes, refractory anemia with ringed sideroblasts. Patients with PG and anemia should have bone marrow biopsy if no cause of anemia is readily apparent.
坏疽性脓皮病(PG)是一种疼痛的、通常进展迅速的溃疡性皮肤疾病,常与全身性疾病相关。我们报告一例患有PG及贫血的患者。骨髓活检显示的变化符合骨髓增生异常综合征之一,即伴有环形铁粒幼细胞的难治性贫血。患有PG和贫血的患者,如果贫血原因不明显,应进行骨髓活检。