DeVita M V, Ky A J, Fried K O, Vogel F E, Michelis M F
Department of Medicine, Nephrology Section, and the Departments of Surgery and Radiology, Lenox Hill Hospital, New York, NY, USA.
Am J Kidney Dis. 2000 Oct;36(4):797-803. doi: 10.1053/ajkd.2000.17669.
There is no single effective means of assessing arteriovenous access function, although monitoring hemodialysis venous pressure (VP) or measuring access recirculation may be of some benefit. The present study assesses prospectively the efficacy of following the peak systolic velocity (PSV) as a single measure to detect arteriovenous graft (AVG) stenosis. PSV was measured in 12 patients after new AVG placement and at approximately 2-month intervals. Angiography was also performed after new graft placement and when PSV was elevated to greater than 200 cm/sec, hemodialysis access VP increased to greater than 150 mm Hg on three consecutive readings, or access recirculation increased to greater than 11%. PSV was then compared with results from angiography, VP monitoring, and access recirculation. The 12 patients underwent 34 PSV studies, followed by angiography on 25 occasions. Each patient underwent at least one angiogram. Each abnormal PSV value was confirmed with the finding of stenosis on angiogram, except for two patients with PSVs greater than 400 cm/sec and normal angiography results. VP and recirculation were not elevated. During this period, two patients developed thrombosis of the AVG, and two patients underwent angioplasty with improvement in PSV. We conclude that elevations in PSV measured at the venous anastomosis are an effective means of screening for AVG stenosis, AVG stenosis can occur early after AVG placement, and elevated VP and recirculation are late findings in AVG dysfunction.
尽管监测血液透析静脉压(VP)或测量通路再循环可能会有一些益处,但目前尚无单一有效的方法来评估动静脉通路功能。本研究前瞻性地评估了将收缩期峰值流速(PSV)作为检测动静脉移植物(AVG)狭窄的单一指标的有效性。在12例患者新置入AVG后及大约每2个月的间隔时间测量PSV。在新移植物置入后以及当PSV升高至大于200 cm/秒、血液透析通路VP连续三次读数升高至大于150 mmHg或通路再循环升高至大于11%时,也进行血管造影。然后将PSV与血管造影、VP监测和通路再循环的结果进行比较。这12例患者接受了34次PSV研究,随后进行了25次血管造影。每位患者至少接受了一次血管造影。除了两名PSV大于400 cm/秒且血管造影结果正常的患者外,每个异常PSV值均经血管造影发现狭窄得以证实。VP和再循环未升高。在此期间,两名患者发生了AVG血栓形成,两名患者接受了血管成形术,PSV有所改善。我们得出结论,在静脉吻合口处测量的PSV升高是筛查AVG狭窄的有效方法,AVG狭窄可在AVG置入后早期发生,而VP升高和再循环升高是AVG功能障碍的晚期表现。