Kuriakose M A, Loree T R, Hicks W L, Welch J J, Wang H, DeLacure M D
Division of Head and Neck Surgery and Oncology, Department of Otolaryngology, New York University School of Medicine, New York, NY 10016, USA.
Br J Oral Maxillofac Surg. 2000 Oct;38(5):460-5. doi: 10.1054/bjom.2000.0316.
This retrospective study evaluated tumour volume, estimated by computed tomography (CT), as a predictive factor in carcinoma of the tongue. Tumour volume was measured from pretreatment CT scans of 20 consecutive patients, followed up for at least 3 years, and this measurement was compared with tumour volume estimated from pathological specimens. T-stage and CT-derived tumour volume were compared with the clinical and pathological status of the nodes, and with the outcome of treatment. The measurement of tumour volume derived from CT correlated well with measurements derived from pathological examination, and tumour volume also predicted overall treatment failure. The disease-specific survival rate was 100% for patients with low-volume tumours (<13 cc) compared with 79% for those with stage T1 and T2 tumours.CT is a reliable way of measuring the volume of tumours in carcinoma of the tongue, and tumour volume is useful adjunct to the clinical tumour-node-metastases staging system.
这项回顾性研究评估了通过计算机断层扫描（CT）估算的肿瘤体积，将其作为舌癌的一个预测因素。从20例连续患者的治疗前CT扫描中测量肿瘤体积，这些患者至少随访了3年，并将该测量结果与病理标本估算的肿瘤体积进行比较。将T分期和CT得出的肿瘤体积与淋巴结的临床和病理状态以及治疗结果进行比较。CT得出的肿瘤体积测量值与病理检查得出的测量值相关性良好，并且肿瘤体积也可预测总体治疗失败。肿瘤体积小（<13 cc）的患者疾病特异性生存率为100%，而T1期和T2期肿瘤患者的这一比例为79%。CT是测量舌癌肿瘤体积的可靠方法，肿瘤体积是对临床肿瘤-淋巴结-转移分期系统的有用辅助。
