MMWR Morb Mortal Wkly Rep. 2000 Sep 22;49(37):833-7.
In 1999, 360,076 cases of gonorrhea were reported in the United States (1). Gonorrhea is a major cause of pelvic inflammatory disease, often leading to ectopic pregnancy and infertility, and it can facilitate human immunodeficiency virus (HIV) transmission (2). During the 1980s, resistance to penicillin and tetracycline among gonococcal isolates became widespread; as a result, CDC recommended that other antimicrobial agents be used to treat gonorrhea. This report summarizes investigations of an increase in fluoroquinolone-resistant Neisseria gonorrhoeae in Hawaii and of a cluster of N. gonorrhoeae infections with decreased susceptibility to azithromycin in Missouri.
1999年，美国报告了360,076例淋病病例（1）。淋病是盆腔炎的主要病因，常导致异位妊娠和不孕，并且它可促进人类免疫缺陷病毒（HIV）传播（2）。在20世纪80年代，淋球菌分离株对青霉素和四环素的耐药性变得普遍；因此，美国疾病控制与预防中心（CDC）建议使用其他抗菌药物治疗淋病. 本报告总结了对夏威夷耐氟喹诺酮淋病奈瑟菌增加情况以及密苏里州一群对阿奇霉素敏感性降低的淋病奈瑟菌感染情况的调查。
