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[Participation of phytohemagglutinin-transformed mouse lymphocytes in development of the "graft-versus-host" reaction].

作者信息

Nesterenko V G, Koval'chuk L V

出版信息

Biull Eksp Biol Med. 1976 Sep;82(9):1096-8.

PMID:11013
Abstract

Transformed lymphocytes obtained as a result of phytohemagglutinin-stimulation of the cells of the lymph nodes of the CBA mice were incapable of realizing the graft-versus-host reaction in administration to the sublethally irradiated (CBAXC57BL/6) F1 hybrids. In this case the graft-versus-host reaction is induced by small untransformed lymphocytes with the same concentration of surface antigens detected by the antilymphocytic serum as in the intact lymphocytes.

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