Olivé G, Buti M, Ignacio Esteban J, Cotrina M, Esteban R, Guardia J
Servicio de Hepatología. Hospital General Universitario Vall d'Hebron. Barcelona.
Med Clin (Barc). 2000 Sep 9;115(7):254-5. doi: 10.1016/s0025-7753(00)71525-9.
Patients with chronic hepatitis are in risk to acquire a fulminant hepatitis associated with hepatitis A virus superinfection.
Antibodies against hepatitis A were study in serum from 353 patients with chronic hepatitis B or C.
The prevalence of IgG-HAV antibodies was 81% in chronic hepatitis C patients, and 77% in chronic hepatitis B patients. The presence of anti-HAV antibodies was related to the patients' age. None case of acute hepatitis A in chronic hepatitis patients was detected.
The prevalence of anti-HAV antibodies is high in patients with chronic viral hepatitis but the incidence of the disease is low. Hepatitis A vaccination should do with previously screening.