David K P, O'Hare M R, Skinhøj P
Ugeskr Laeger. 2000 Sep 18;162(38):5074-7.
Dengue fever is a major cause of febrile illness in the tropics, and we describe 44 patients with dengue fever seen at Rigshospitalet, Copenhagen from 1988-98. A worldwide increase in transmission of dengue fever was reflected in the number of patients seen in 1997-1998. All patients had fever and headache, and were biochemically characterised by thrombocytopenia, leucopenia, increased levels of alanine aminotransferase and a rise in haematocrit. One patient had dengue haemorrhagic fever, and two patients exhibited unusual reactions to the infection, one in the form of extended febrile neutropenia complicated by an episode of of E. coli septicaemia, and one patient developed progressive paralysis of both legs, and remains partially paretic.
登革热是热带地区发热性疾病的主要病因，我们描述了1988年至1998年在哥本哈根里格霍斯医院就诊的44例登革热患者。1997年至1998年就诊患者数量反映出登革热在全球范围内传播的增加。所有患者均有发热和头痛症状，生化特征为血小板减少、白细胞减少、丙氨酸转氨酶水平升高和血细胞比容升高。1例患者患有登革出血热，2例患者对感染表现出异常反应，1例表现为持续性发热性中性粒细胞减少并伴有大肠杆菌败血症发作，另1例患者出现双下肢进行性麻痹，仍有部分瘫痪。
