Bianco J A, Shafer R B
Am J Med Sci. 1979 May-Jun;277(3):244-54. doi: 10.1097/00000441-197905000-00001.
The recent introduction of newer scintillation cameras, convenient radiopharmaceuticals and innovative data-processing systems has hastened the use of radionuclide methods in the evaluation of cardiac function. This review familiarizes the primary internist with physics and instrumentation required in understanding cardiovascular nuclear images. Basic principles underlying the gated cardiac blood-pool scan and the first-pass study are described. Authoritative references are given to readers seeking more complete information. The major emphasis of the review, however, is on the clinical applications of these techniques. The role of these noninvasive methods in myocardial infarction, diagnosis and prognosis of ischemic heart disease, assessment of cardiomyopathies, study of idiopathic hypertrophic subaortic stenosis and left atrial myxoma is discussed. Finally, mention is made of newer applications: evaluation of nitroglycerin action on viable but ischemic myocardium and determination of the hemodynamic effects of propranolol in patients with coronary-artery disease.
最近，更新型的闪烁照相机、便捷的放射性药物和创新的数据处理系统的引入，加速了放射性核素方法在心脏功能评估中的应用。这篇综述使初级内科医生熟悉理解心血管核素图像所需的物理学和仪器设备知识。描述了门控心血池扫描和首次通过研究的基本原理。为寻求更完整信息的读者提供了权威参考文献。然而，该综述的主要重点是这些技术的临床应用。讨论了这些非侵入性方法在心肌梗死、缺血性心脏病的诊断和预后、心肌病评估、特发性肥厚性主动脉瓣下狭窄和左心房黏液瘤研究中的作用。最后，提到了一些新的应用：评估硝酸甘油对存活但缺血心肌的作用以及确定普萘洛尔对冠心病患者的血流动力学影响。
