Gryschek G
Acta Biol Med Ger. 1975;34(1):155-61.
Adult mice react with an increased production of PFC (plaque-forming cells) against sheep erythrocytes (SE). in the primary immune response after application of BCG. Animals receiving 0,5 mg of BCG 10 days before SE show an increase in direct PFC of more than 50%. No effect was observed after injecting BCG 14 or 5 days before SE or using a dose of 0,1 mg of BCG. The results indicate that the effect of BCG on the humoral immune response is influenced by the interval between application of BCG and the SE as well as the BCG-dose. By contrast, BCG had no significant influence on the secondary humoral immune response. In a few cases the immune response seemed to be suppressed.
成年小鼠在接种卡介苗（BCG）后，针对绵羊红细胞（SE）的原发性免疫反应中，其形成斑块细胞（PFC）的产量会增加。在接种SE前10天接受0.5毫克卡介苗的动物，其直接PFC增加超过50%。在接种SE前14天或5天注射卡介苗或使用0.1毫克卡介苗剂量后未观察到效果。结果表明，卡介苗对体液免疫反应的影响受卡介苗与SE接种间隔以及卡介苗剂量的影响。相比之下，卡介苗对继发性体液免疫反应没有显著影响。在少数情况下，免疫反应似乎受到抑制。
