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[一例肺癌支气管残端复发患者采用顺铂联合长春瑞滨同步放化疗成功治疗的病例]

[A case of bronchial stump recurrence of lung cancer successfully treated with chemoradiotherapy using cisplatin plus vinorelbine].

作者信息

Endo C, Yoshida H, Suda H

机构信息

Dept. of Thoracic Surgery, Ohta Nishinouchi Hospital.

出版信息

Gan To Kagaku Ryoho. 2000 Sep;27(10):1569-72.

Abstract

A 61-year-old man, who had undergone right upper lobectomy for lung cancer about nineteen months earlier, was examined at our hospital for hemoptysis. A bronchial stump recurrence was observed by chest CT and bronchoscopy. The patient underwent chemoradiotherapy using cisplatin (CDDP) and vinorelbine (VNB). Irradiation was started (total 60 Gy/30 fr/6 weeks) about four weeks before the onset of chemotherapy. Chemotherapy consisted of 2 cycles of CDDP 80 mg/m2 on day 1 and VNB 15 mg/m2 on day 1, 8. The dose of VNB was increased to 25 mg/m2 during cycle 2 because cycle 2 was without radiotherapy. After the chemoradiotherapy, the recurrent tumor disappeared on a CT scan and bronchoscopy. Chemoradiotherapy using CDDP plus VNB regimen is considered effective, without serious side effects for advanced non-small-cell lung cancer.

摘要

一名61岁男性,约19个月前因肺癌接受了右上叶切除术,因咯血到我院就诊。胸部CT和支气管镜检查发现支气管残端复发。该患者接受了使用顺铂(CDDP)和长春瑞滨(VNB)的放化疗。放疗在化疗开始前约四周开始(总量60 Gy/30次/6周)。化疗包括第1天给予2个周期的CDDP 80 mg/m²和第1、8天给予VNB 15 mg/m²。由于第2周期未进行放疗,VNB剂量在第2周期增加至25 mg/m²。放化疗后,复发肿瘤在CT扫描和支气管镜检查中消失。对于晚期非小细胞肺癌,使用CDDP加VNB方案的放化疗被认为是有效的,且无严重副作用。

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