Norn M S
Acta Ophthalmol (Copenh). 1975 Jun;53(3):450-7.
A total of 209 pathological eyes each had 17 localities tested for sensitivity (cornea, caruncle, upper and lower lid margins (centrally, medially and laterally), and corresponding localities on the palpebral conjunctiva, and upper and lower halves of the bulbar conjunctiva). Reduced conjunctival sensitivity is seen in pemphigoid (excluding the lid margin) in contact lens wearers, at sites of nerves transected during operation and in rare cases of infectious conjunctivitis. Isolated corneal hypaesthesia is seen in bacterial or fungal keratitis. In herpes, the hypaesthesia extends over the bulbar conjunctiva, in zoster, over wider areas (including the lid margin). The sensitivity is normal in keratoconjunctivitis sicca and chronic conjunctivitis. In neurological diseases the hyposensitivity could include the cornea, conjunctiva and lid margin. The conclusion is drawn that a study of the conjunctivo-corneal sensitivity can give differential diagnostic information, provided the normal sensitivity range is known. This has been set out in a Table in 10-year age groups.
共有209只患眼，每只眼对17个部位进行了敏感性测试（角膜、泪阜、上下睑缘（中央、内侧和外侧）、睑结膜相应部位以及球结膜上下半部）。在类天疱疮（不包括睑缘）的隐形眼镜佩戴者、手术中神经横断部位以及罕见的感染性结膜炎病例中可见结膜敏感性降低。在细菌性或真菌性角膜炎中可见孤立的角膜感觉减退。在疱疹中，感觉减退累及球结膜，在带状疱疹中，累及范围更广（包括睑缘）。在干燥性角结膜炎和慢性结膜炎中敏感性正常。在神经疾病中，感觉减退可能包括角膜、结膜和睑缘。得出的结论是，只要知道正常敏感性范围，结膜-角膜敏感性研究就能提供鉴别诊断信息。这已按10岁年龄组列于表格中。
