Mirz F, Zachariae B, Andersen S E, Nielsen A G, Johansen L V, Bjerring P, Pedersen C B
Arhus Universitetshospital, Arhus Kommunehospital, øre-naese-halsafdeling H.
Ugeskr Laeger. 2000 Jun 19;162(25):3607-10.
This study evaluated the effect of low-power laser in the treatment of tinnitus in a randomized, prospective, double-blind, placebo-controlled trial. The active laser applied 50 mW (cw, 830 nm) over a period of 10 minutes per session. Forty-nine patients were included. The main outcome was measured using psychoacoustical match of tinnitus loudness, Visual Analog Scale (VAS) ratings of subjective loudness, annoyance and attention involved, scores on tinnitus-specific questionnaires, and a number of psychosocial questionnaires. Only few subjects (18%) experienced subjective improvement. There were no statistically significant differences between the effects of the active laser and placebo treatments.
Low-power laser treatment is not indicated in the treatment of tinnitus. Reports of significant benefits of this treatment in previous studies may be explained by the placebo effect.
本研究在一项随机、前瞻性、双盲、安慰剂对照试验中评估了低功率激光治疗耳鸣的效果。活性激光每次照射10分钟，功率为50毫瓦（连续波，830纳米）。纳入了49名患者。主要结局通过耳鸣响度的心理声学匹配、主观响度的视觉模拟量表（VAS）评分、所涉及的烦恼和注意力、耳鸣特异性问卷得分以及一些心理社会问卷进行测量。只有少数受试者（18%）经历了主观改善。活性激光治疗与安慰剂治疗的效果之间没有统计学上的显著差异。
低功率激光治疗不适用于耳鸣治疗。先前研究中关于这种治疗有显著益处的报告可能是由安慰剂效应解释的。
