Lazarus G S, Poole A R
Arch Dermatol. 1975 Sep;111(9):1150-3.
The lysosomal proteinase cathepsin D has been localized in rabbit skin by immunocytochemical techniques. The enzyme was found in the basal layer of the epidermis, hair follicles, sebaceous glands, fibroblasts, and endothelial cells. An autoradiographic technique, using the Fab' fragment of IgG, was also used for more effective identification of cell types that contain cathepsin D.
溶酶体蛋白酶组织蛋白酶D已通过免疫细胞化学技术定位在兔皮肤中。该酶存在于表皮的基底层、毛囊、皮脂腺、成纤维细胞和内皮细胞中。一种使用IgG的Fab'片段的放射自显影技术也被用于更有效地识别含有组织蛋白酶D的细胞类型。
