Riechmann J L, Ratcliffe O J
Mendel Biotechnology, Hayward, California 94545, USA.
Curr Opin Plant Biol. 2000 Oct;3(5):423-34. doi: 10.1016/s1369-5266(00)00107-2.
Data from the Arabidopsis genome project suggest that more than 5% of the genes of this plant encode transcription factors. The necessity for the use of genomic analytical approaches becomes clear when it is considered that less than 10% of these factors have been genetically characterized. A variety of tools for functional genomic analyses in plants have been developed over the past few years. The availability of the full complement of Arabidopsis transcription factors, together with the results of recent studies that illustrate some of the challenges to their functional characterization, now provides the basic framework for future analyses of transcriptional regulation in plants.
来自拟南芥基因组计划的数据表明,这种植物超过5%的基因编码转录因子。考虑到这些因子中不到10%已通过遗传学方法鉴定其特征,就会清楚地认识到使用基因组分析方法的必要性。在过去几年中,已经开发出了多种用于植物功能基因组分析的工具。拟南芥转录因子的完整集合,以及最近一些研究所展示的对其功能特征鉴定的挑战,为今后植物转录调控分析提供了基本框架。