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羟基磷灰石听骨链假体的评估

Evaluation of hydroxyapatite ossicular chain prostheses.

作者信息

Pasha R, Hill S L, Burgio D L

机构信息

Department of Otolaryngology-Head and Neck Surgery, Wayne State University, USA.

出版信息

Otolaryngol Head Neck Surg. 2000 Oct;123(4):425-9. doi: 10.1067/mhn.2000.109369.

Abstract

Hydroxyapatite (HA) middle ear prostheses have gained popularity as an alternative to human autografts and homografts. This study reports on 3 HA prostheses types: total ossicular chain prostheses, used for grafting the stapes footplate to the tympanic membrane; partial ossicular chain prostheses, used for grafting the stapes superstructure to the tympanic membrane; and Kartush incus struts (Smith & Nephew Richards Inc), used for grafting the stapes superstructure to the undersurface of the malleus. This single-surgeon study of 33 consecutive cases revealed a statistically significant difference in mean postoperative air-bone gap and airbone gap closure between incus struts (14/26 dB) or partial (22/11 dB) or total (25/10 dB) ossicular chain prostheses (t test: P<0.05). Prognostic risk factors graded by the Middle Ear Risk Index indicate a tendency for worse postoperative hearing with increasing Middle Ear Risk Index. This study supports the use of HA ossicular prostheses and, in particular, the use of the malleus for ossicular chain construction.

摘要

羟基磷灰石(HA)中耳假体作为自体移植和同种异体移植的替代物已越来越受欢迎。本研究报告了3种HA假体类型:全听骨链假体,用于将镫骨足板移植至鼓膜;部分听骨链假体,用于将镫骨上部结构移植至鼓膜;以及Kartush砧骨支柱(史赛克理查兹公司),用于将镫骨上部结构移植至锤骨下表面。这项由单一外科医生进行的对33例连续病例的研究显示,砧骨支柱(14/26分贝)、部分(22/11分贝)或全(25/10分贝)听骨链假体术后平均气骨导间距和气骨导间距闭合存在统计学显著差异(t检验:P<0.05)。根据中耳风险指数分级的预后危险因素表明,随着中耳风险指数增加,术后听力有变差的趋势。本研究支持使用HA听骨假体,特别是利用锤骨进行听骨链重建。

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