Basaria S, McCarthy E F, Belzberg A J, Ball D W
Division of Endocrinology and Metabolism, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
J Endocrinol Invest. 2000 Sep;23(8):533-5. doi: 10.1007/BF03343770.
The differential diagnosis of an osteoblastic vertebral lesion (ivory vertebra) includes metastatic prostate cancer, lung cancer, lymphoma, osteosarcoma and Paget's disease. We report a case of a man who was initially diagnosed with Paget's disease on vertebral biopsy. He failed to respond to conventional bisphosphate therapy. The review of the original biopsy specimen showed metastatic carcinoid tumor involving the bone marrow. The various features of carcinoid tumors metastasizing to the skeleton are briefly reviewed.
成骨性椎体病变(象牙椎)的鉴别诊断包括前列腺癌转移、肺癌、淋巴瘤、骨肉瘤和佩吉特病。我们报告一例男性患者,其最初经椎体活检诊断为佩吉特病。他对传统双膦酸盐治疗无反应。对原始活检标本的复查显示骨髓受累的转移性类癌肿瘤。本文简要回顾了类癌肿瘤转移至骨骼的各种特征。