Gill J
Department of Occupational Therapy and Art Therapy, Queen Margaret University College, Duke Street, Edinburgh EH8 6HF, UK.
Alcohol Alcohol. 2000 Sep-Oct;35(5):417-23. doi: 10.1093/alcalc/35.5.417.
Studies that have investigated the effect of moderate alcohol consumption on the level of oestrogens and progesterone in both pre- and post-menopausal women are reviewed. It is concluded that several lines of evidence point to an alcohol-induced rise in natural or synthetic oestrogen levels in women. Proposed mechanisms include an increased rate of aromatization of testosterone or a decreased rate of oxidation of oestradiol to oestrone. Moderate alcohol consumption has also been linked to decreased progesterone levels in pre-menopausal women. The relevance of these findings to female health, fertility and the timing of the menopause is considered.
本文综述了多项研究,这些研究调查了适度饮酒对绝经前和绝经后女性雌激素和孕酮水平的影响。研究得出结论,有几条证据表明,饮酒会导致女性体内天然或合成雌激素水平升高。提出的机制包括睾酮芳构化速率增加或雌二醇向雌酮的氧化速率降低。适度饮酒还与绝经前女性孕酮水平降低有关。本文还探讨了这些发现与女性健康、生育能力和绝经时间的相关性。