Groh M J, Behrens A, Händel A, Küchle M
Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg.
Klin Monbl Augenheilkd. 2000 Aug;217(2):71-6. doi: 10.1055/s-2000-10387.
To determine success rate of trabeculotomy in patients with juvenile and late-juvenile glaucoma in a retrospective study.
46 eyes of 41 juvenile glaucoma-patients (24 female, 17 male) were submitted to trabeculotomy during the period of 1980-1997. Patients age at the time of surgery was 30.2 +/- 10.5 years (11-49 years, median 21 years). Follow-up time was 35 +/- 46 months (1-155 months).
Median preoperative visual acuity was 1.0 (range 0.002 to 1.25), postoperative visual acuity at the end of the follow up period was 0.8 (median) with a range from 0.002 to 1.2. In all patients preoperative intraocular pressure was elevated and a glaucomatous configuration of the optic disc was noticed. Preoperative intraocular pressure (IOP) ranged from 30.5 +/- 13.2 mm Hg, after surgery IOP was 16.2 +/- 5 mm Hg. Mean decrease of the IOP postoperatively was 54.4%. In 37% of the eyes IOP was lower than 23 mm Hg without additional medication, in 47% of the eyes IOP was lower than 23 mm Hg with additional medication. In 8 eyes additional antiglaucoma-surgery was necessary. After a follow-up time of 60 months 81% of the patients (n = 37 eyes) had an IOP below 23 mm Hg, after 120 months in 80% of the patients (n = 29 eyes) IOP was below 23 mm Hg.
The success rate of trabeculotomy (defined as the ability to lower intraocular pressure lower than 23 mm Hg with or without antiglaucoma medication) in our patients is 84%. After second operation, success rate is 89%. Trabeculotomy for patients with juvenile open angle glaucoma is a safe procedure and avoids problems and complications of filtering procedures.
在一项回顾性研究中确定小梁切开术治疗青少年及青少年晚期青光眼患者的成功率。
1980年至1997年期间,对41例青少年青光眼患者(24例女性,17例男性)的46只眼进行了小梁切开术。手术时患者年龄为30.2±10.5岁(11至49岁,中位数21岁)。随访时间为35±46个月(1至155个月)。
术前视力中位数为1.0(范围0.002至1.25),随访期末术后视力中位数为0.8,范围为0.002至1.2。所有患者术前眼压均升高,且视盘呈青光眼性形态。术前眼压(IOP)范围为30.5±13.2 mmHg,术后眼压为16.2±5 mmHg。术后眼压平均降低54.4%。37%的眼在未使用其他药物情况下眼压低于23 mmHg,47%的眼在使用其他药物情况下眼压低于23 mmHg。8只眼需要额外的抗青光眼手术。随访60个月后,81%的患者(n = 37只眼)眼压低于23 mmHg,随访120个月后,80%的患者(n = 29只眼)眼压低于23 mmHg。
我们患者中小梁切开术的成功率(定义为无论是否使用抗青光眼药物眼压能降至23 mmHg以下的能力)为84%。二次手术后,成功率为89%。青少年开角型青光眼患者的小梁切开术是一种安全的手术,可避免滤过手术的问题和并发症。