Chai L, Ong K C, Ng S B
Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.
Respirology. 2000 Sep;5(3):297-9. doi: 10.1046/j.1440-1843.2000.00262.x.
Pulmonary metastases from choriocarcinoma can very rarely give rise to a 'miliary' pattern on the chest X-ray. A 23-year-old woman with a diffuse nodular pattern on chest X-ray died due to acute respiratory failure and cor pulmonale. At autopsy, choriocarcinoma of the uterus was found. In the lungs, multiple macrovascular tumour emboli within branches of pulmonary muscular arteries in the region of segmental/subsegmental bronchi were detected. There was no evidence of pulmonary parenchymal metastases, pneumonia or tuberculosis. The 'miliary' pattern of pulmonary metastases described in cases of choriocarcinoma may be due to large vessel intra-arterial tumour emboli rather than disseminated parenchymal metastases.
绒毛膜癌的肺转移在胸部X线片上极少呈现“粟粒状”表现。一名23岁女性胸部X线片显示弥漫性结节状影,死于急性呼吸衰竭和肺心病。尸检发现子宫绒毛膜癌。在肺内,于段/亚段支气管区域的肺肌性动脉分支内检测到多个大血管肿瘤栓子。未发现肺实质转移、肺炎或结核的证据。绒毛膜癌病例中所描述的肺转移“粟粒状”表现可能是由于大血管动脉内肿瘤栓子,而非播散性实质转移。